Curriculum Vitae Judith Klumperman

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Biographical sketch

Judith Klumperman (1961) studied Biology at Leiden University. In 1990 she obtained her PhD from the Laboratory for Electron Microscopy, Medical Faculty, University of Leiden (Promotor: Prof. W.Th. Daems) and the Department for Biochemistry, Academic Medical Centre, University of Amsterdam (Promotor: Prof. J.M. Tager) in a collaborative project with the Biocenter in Basel, Switzerland (Prof. H.P. Hauri) on the ‘Transport of lysosomal and brush border enzymes in polarized colon carcinoma cell lines’.

In 1989, she accepted a postdoc position at the Department of Cell Biology, Center for Electron Microscopy, Medical Faculty, University Medical Center (UMC) Utrecht (Prof. J.J. Geuze), where she worked on the ‘Cellular transport mechanisms of lysosomal enzymes’, in collaboration with the Department of Biochemistry in Göttingen, Germany (Prof. K. von Figura),

In 1992, she became a tenured assistant professor at the Department of Molecular and Cellular Neurobiology, Faculty Biology, Free University, Amsterdam. In 1999, she returned to the Department of Cell Biology, UMC Utrecht, where in 2001 she became full professor of Cell Biology and in 2007 Head of the Department. In 2009 she founded the 'Cell Screening Core' for high throughput/high content analysis.

Professional career

1985-1989. PhD student, Laboratory for Electron Microscopy, Medical Faculty, University of Leiden, The Netherlands
1989-1992. Postdoctoral fellow, Department of Cell Biology, Center for Electron Microscopy, University Medical Center (UMC) Utrecht, The Netherlands.
1992 – 1997 Assistant professor (tenured), Department of Molecular and Cellular Neurobiology, Faculty Biology, Free University (VU), Amsterdam, The Netherlands.
1997 - 1999: Assistant professor (tenured), Department of Cell Biology, UMC Utrecht, The Netherlands
1999 – 2001. Associate professor, Department of Cell Biology, UMC Utrecht, The Netherlands.
2001 – current. Full Professor, Department of Cell Biology, UMC Utrecht, The Netherlands. Chair Cell Microscopy Core UMC Utrecht.
2009 – current. Department Head, Department of Cell Biology, UMC Utrecht, The Netherlands. Chair Cell Screening Core UMC Utrecht.

Awards and honors

1998: UMC Utrecht Attraction and maintenance of female talent grant
2004. ZonMW VICI award. Defining novel pathways of lysosome biogenesis: a genome-wide screen combined with correlative microscopy.
2007. 20th Foundation lecture of the Center for Cell and Molecular Biology, Hyderabad, India
2008. Elected EMBO member (European Molecular Biology Organization)
2012: AcademiaNet. Robert Bosch Stiftung expert database of outstanding Female Scientists and Scholars

Financial support

1996: NWO/Stichting Levenswetenschappen project grant
1998: UMC Utrecht Attraction and maintenance of female talent grant.
2000: NWO/ALW project grant
2000: FOM open project Grant (with Dr. A.J. Koster, UU)
2001– present: Genentech Collaborative Projects
2002: ISAO Award (International Foundation Alzheimer Research) (with Prof. W. Annaert, University of Leuven, Belgium).
2003: ZonMW investment grant (with Dr. J.L. Bos, UMC Utrecht)
2004: Intra-European Marie-Curie Fellowship
2004: ZonMW VICI award:
2005: Horizon Breakthrough.
2005 UMC Utrecht Grant for improvement international collaborations (with Dr. R. Pepperkok, EMBL, Germany)
2007: ZonMW investment grant (with Dr. F. Reggiori, UMC Utrecht)
2008 UMC Utrecht Grant for improvement international collaborations (with Dr. S. Kornfeld, Washington University, StLouis, USA))
2008 Utrecht University short stay fellowships (with Dr. S. Mayor, NCBS, Bangalore, India)
2009: Utrecht University short Stay Fellowship (with Dr. R Edwards, University of California, San Francisco, USA).
2010: STW open technology program. (with Dr. G.J.A.M. Strous and Dr. D. Egan, UMC Utrecht)
2010: EU 7th FRAMEWORK PROGRAMME Research infrastructure for imaging technologies in biological and biomedical sciences. EuroBioImaging Prepratory phase. Coordinator Workpackage correlative microscopy (CLEM).
2013: STW perspective grant: Development of CLEM techniques. (Co-applicant, subproject leader)
2014: Enabling technologies. NWO/ZonMW (with Dr. D. Egan and Drs. W. Omta)
2014: International Foundation Alzheimer Research (with Dr. W. Scheper, VUMC Amsterdam).

Research interests

endosomal system
lysosome biogenesis
correlative microscopy
cancer
stem cells
neurological disorders

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