Curriculum Vitae Fulvio Reggiori

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Biographical sketch

Fulvio Reggiori (1970) studied Biochemistry at University of Fribourg, Switzerland, and in 1997, he obtained his PhD in Biochemistry from the same Institution. Here, in the laboratory of Prof. Andreas Conzelmann, he has worked on the remodeling of the lipid moiety of GPI-anchored proteins and on sphingolipid biosynthesis in yeast Saccharomyces cerevisiae.

After staying one additional year in the same laboratory as a postodoctoral fellow, in 1998, he moved to the MRC Laboratory of Molecular Biology in Cambridge, United Kingdom. There, in the laboratory of Dr. Hugh Pelham, he has investigated the signals targeting integral membrane proteins into the internal vesicles of multivesicular bodies. He characterized ubiquitin-dependent and independent signals, and identified one of the ubiquitin ligases specifically involved in this pathway.

In 2001, he joined the laboratory of Prof. Daniel Klionsky at the Life Sciences Institute of the Michigan University of Michigan in Ann Arbor (USA). There, he started working on different aspects of the molecular mechanism of autophagy in yeast. In particular, he first described the dynamic trafficking of Atg9 and show the involvement in this process of proteins such as Atg1, Atg2, Atg13 and Atg18, and phosphatidylinositol-3-phosphate.

In 2005, Fulvio Reggiori became a tenured Assistant Professor at the Department of Cell Biology of the University Medical Center Utrecht, where he is working on the molecular mechanism and regulation of autophagy using yeast Saccharomyces cerevisiae as a model organism. The laboratory interests are also on pathogens that subvert autophagy to invade and replicate in host cells and a particular research focus has been coronaviruses. Since September 2011, he is an Associate professor at the same Institution.

Professional career

1994-1997. PhD study at the Department of Biochemistry of the University of Fribourg, Switzerland (Supervisor: Prof. A. Conzelmann).
1997-1998. Postdoctoral fellow at the Department of Biochemistry of the University of Fribourg, Switzerland, with Prof. Andreas Conzelmann.
1998 – 2001. Postdoctoral fellow in the MRC Laboratory of Molecular Biology Cambridge, United Kingdom, with Dr. Hugh R.B. Pelham.
2001 – 2005. Postdoctoral fellow at the Life Sciences Institute and the Department of Molecular, Cellular, and Developmental Biology of the University of Michigan, Ann Arbor, United States of America, with Prof. Daniel Klionsky.
2005 – 2011. Tenured assistant professor at the Department of Cell Biology of the University Medical Center Utrecht, The Netherlands.
2011 - current. Associate professor at the Department of Cell Biology of the University Medical Center Utrecht, The Netherlands.

Awards and honors

1993-1994. CIBA-GEIGY prize for the best 1993/1994 graduation curriculum in chemistry and biochemistry at the University of Fribourg.
1998-1999. Swiss National Science Foundation fellowship
1999-2001. EMBO long-term fellowship
2001-2002. EMBO long-term fellowship
2002-2004. Swiss National Science Foundation fellowship for advanced researchers

Financial support

2006. Utrecht University High Potential grant (with Dr. Xander de Haan)
2006. ZonMW VIDI grant
2007. ZonMW Medium Investment grant
2007. ALW Open Program grant
2010. CW ECHO grant (with Prof. Bernd Helms)
2010. NWO-DFG bilateral programme grant (with Prof. Christian Ungermann)
2011. ALW Open Program grant
2012. ALW Open Program grant
2013. ZonMW VICI grant
2014. Sinergia grant from SNSF (with prof. Matthias Peter and Maurizio Molinari)

Research interests

autophagy
endosomal system
autophagy and infections

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