Publication Archive


Publication year 2021

19. Calandrini C., van Hooff S.R., Paassen I., Ayyildiz D., Derakhshan S., Dolman MEM, Langenberg K.P.S., van de Ven M., de Heus C., Liv N., Kool M., de Krijger R.R., Tytgat G.A.M., van den Heuvel-Eibrink M.M., Molenaar J.J., Drost J (2021). Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors, Cell Rep, 36 (8):109568.

18. Pizette, S., Matusek, T., Herpers, B., Thérond, P. P. & Rabouille, C. (2021) Hherisomes, Hedgehog specialized recycling endosomes, are required for high level Hedgehog signaling and tissue growth, Journal of cell science, 134, 10, jcs258603.

17. Zhang, C., van Leeuwen, W., Blotenburg, M., Aguilera-Gomez, A., Brussee, S., Grond, R., Kampinga, H. H. & Rabouille, C. (2021) Activation of IRE1, PERK and salt-inducible kinases leads to Sec body formation in Drosophila S2 cells, Journal of cell science, 134, 17.

16. Venhuizen, A. J., van der Krift, F. & Maurice, M. M. (2021), Building a complex for destruction, Molecular Cell, 81 (16): 3241-3243 3.

15. Pascual, R., Segura-Morales, C., Omerzu, M., Bellora, N., Belloc, E., Castellazzi, C. L., Reina, O., Eyras, E., Maurice, M. M.(2021), Millanes-Romero, A. & Méndez, R. (2021), mRNA spindle localization and mitotic translational regulation by CPEB1 and CPEB4, RNA, 27 (3):291-302 12.

14. Gao, X., Mazière, A. D., Beard, R., Klumperman, J. & Hannoush, R. N., (2021), Fatty acylation enhances the cellular internalization and cytosolic distribution of a cystine-knot peptide, iScience, 24 (11): 103220.

13. Tran, N-H., Carter, S. D., De Mazière, A., Ashkenazi, A., Klumperman, J. Walter, P. & Jensen, G. J., (2021), The stress-sensing domain of activated IRE1? forms helical filaments in narrow ER membrane tubes, Science, 374 (656): 52-57 6.

12. Jonker, C. T. H., Galmes, R., Veenendaal, T., Ten Brink, C., van der Welle, R. E. N., Liv, N., de Rooij, J., Peden, A. A., van der Sluijs, P., Margadant, C. & Klumperman, J. (2021), Author Correction: Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions, Nature Communications, 12 (1): 5828.

11. Klumperman, J. & Pucadyil, T. (2021), Understanding membrane traffic from molecular ensemble, energetics, and the cell biology of participant components, Current Opinion in Cell Biology, (71): iii-vi.

10. Özkan, N., Koppers, M., van Soest, I., van Harten, A., Jurriens, D., Liv, N., Klumperman, J., Kapitein, L. C., Hoogenraad, C. C. & Farías, G. G., (2021), ER - lysosome contacts at a pre-axonal region regulate axonal lysosome availability, Nature Communications, 12 (1): 4493.

9. Jamalpoor, A., van Gelder, C. A., Yousef Yengej, F. A., Zaal, E. A., Berlingerio, S. P., Veys, K. R., Pou Casellas, C., Voskuil, K., Essa, K., Ammerlaan, C. M., Rega, L. R., van der Welle, R. E., Lilien, M. R., Rookmaaker, M. B., Clevers, H., Klumperman, J. Levtchenko, E., Berkers, C. R., Verhaar, M. C., (2021), Cysteamine-bicalutamide combination therapy corrects proximal tubule phenotype in cystinosis, Embo Molecular Medicine,13 (7): e13067.

8. Dilsizoglu Senol, A., Samarani, M., Syan, S., Guardia, C. M., Nonaka, T., Liv, N., Latour-Lambert, P., Hasegawa, M., Klumperman, J., Bonifacino, J. S. & Zurzolo, C., (2021) α-Synuclein fibrils subvert lysosome structure and function for the propagation of protein misfolding between cells through tunneling nanotubes, PLoS Biology, 19 (7): e3001287.

7. Bugter J.M., Fenderico N., Maurice M.M. (2021) Publisher Correction: Mutations and mechanisms of WNT pathway tumour suppressors in cancer, Nat Rev Cancer, (1):64 1.

6. Sprangers J., Zaalberg I.C., Maurice M.M. (2021) Organoid-based modeling of intestinal development, regeneration, and repair, Cell Death Differ, 2021 Jan;28(1):95-107.

5. Bugter J.M., Fenderico N., Maurice M.M. (2021) Mutations and mechanisms of WNT pathway tumour suppressors in cancer, Nat Rev Cancer, (1):5-21.

4. Hansen M.B., Postol M., Tvingsholm S., Nielsen I.Ø., Dietrich T.N., Puustinen P., Maeda K., Dinant C., Strauss R., Egan D, Jäättelä M., Kallunki T (2021) Identification of lysosome-targeting drugs with anti-inflammatory activity as potential invasion inhibitors of treatment resistant HER2 positive cancers, Cell Oncol (Dordr), :1-16.

3.van der Welle R.E.N, Jobling R., Burns C., Sanza P., van der Beek J.A., Fasano A., Chen L., Zwartkruis F.J., Zwakenberg S., Griffin E.F., Ten Brink C., Veenendaal T., Liv N., van Ravenswaaij-Arts C.M.A., Lemmink HH, Pfundt R., Blaser S., Sepulveda C., Lozano A.M., Yoon G., Santiago-Sim T., Asensio C.S., Caldwell G.A., Caldwell K.A., Chitayat D., Klumperman J. (2021) Neurodegenerative VPS41 variants inhibit HOPS function and mTORC1-dependent TFEB/TFE3 regulation, EMBO Mol Med, 13(5):e13258 .

2. Lane R., Vos Y., Wolters A.H.G., Kessel L.V., Chen S.E., Liv N., Klumperman J., Giepmans B.N.G., Hoogenboom J.P.(2021) Optimization of negative stage bias potential for faster imaging in large-scale electron microscopy, J Struct Biol X.;5:100046.

1. Burns C.H., Yau B., Rodriguez A., Triplett J., Maslar D., An Y.S., van der Welle R.E.N., Kossina R.G., Fisher M.R., Strout G.W., Bayguinov P.O., Veenendaal T., Chitayat D., Fitzpatrick J.A.J., Klumperman J., Kebede M.A., Asensio C.S. (2021) Pancreatic ß-Cell-Specific Deletion of VPS41 Causes Diabetes Due to Defects in Insulin Secretion, Diabetes, 70(2):436-448.