Publications Judith Klumperman

Key publications (for the complete list click here)

Klumperman J, Raposo G. (2014) The Complex Ultrastructure of the Endolysosomal System. Cold Spring Harb Perspect Biol, Eds. S. Schmid, A. Sorkin. M. Zerial.

Wiegerinck CL, Janecke AR, Schneeberger K, Vogel GF, van Haaften-Visser DY, Escher JC, Adam R, Thöni CE, Pfaller K, Jordan AJ, Weis CA, Nijman IJ, Monroe GR, van Hasselt PM, Cutz E, Klumperman J, Clevers H, Nieuwenhuis EE, Houwen RH, van Haaften G, Hess MW, Huber LA, Stapelbroek JM, Müller T, Middendorp S. (2014) Loss of Syntaxin 3 Causes Variant Microvillus Inclusion Disease. Gastroenterology, 147, 65-68.

Nakamura N, Lill JR, Phung Q, Jiang Z, Bakalarski C, de Mazière A, Klumperman J, Schlatter M, Delamarre L, Mellman I. (2014) Endosomes are specialized platforms for bacterial sensing and NOD2 signalling. Nature, 509, 240-4.

Pols M, van Meel E, Oorschot V, ten Brink C, Fukuda M, Swetha MG, Mayor S, Klumperman J (2013), hVps41 and VAMP7 function in direct TGN to late endosome transport of lysosomal membrane proteins, Nat Comm, 4, 1361.

Pols MS, ten Brink C, Gosavi P, Oorschot V, Klumperman J (2013), The HOPS proteins hVps41 and hVps39 are required for homotypic and heterotypic late endosome fusion, Traffic, 14, 219-32.

Swetha MG, Sriram V, Krishnan KS, Oorschot VMJ, ten Brink C, Klumperman J, Mayor S (2011), Lysosomal protein composition, acidic pH and sterol content are regulated by a light-dependent pathway in metazoan cells, Traffic, 12, 1037-1055.

Judith Klumperman. Architecture of the mammalian Golgi. In: The Golgi book. Cold Spring Harbor editions 2011. Eds. Jim Rothman and G. Warren.

Yu L, McPhee CK, Zheng L, Mardones GA, Rong Y, Peng J, Mi N, Zhao Y, Liu Z, Wan F, Hailey DW, Oorschot V, Klumperman J, Baehrecke EH, Lenardo MJ (2010), Termination of autophagy and reformation of lysosomes regulated by mTOR, Nature, 465, 942-6

Saftig P, Klumperman J (2009), Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function, Nat Rev Mol Cell Biol, 10, 623-35.

van Rijnsoever C, Oorschot V, Klumperman J (2008), A novel correlative light-electron microscopy (CLEM) method integrating live-cell imaging and immunolabeling of ultrathin cryosections, Nature Methods, 5, 973-80.

Zeuschner D, Geerts WJC, van Donselaar E, Humbel B, Slot JW, Koster AJ, Klumperman J (2006), Immuno-electron tomography reveals the existence of free COPII-coated transport carriers, Nat Cell Biol, 8, 377-383.

Rechards M, Xia W, Oorschot V, van Dijk S, Annaert W, Selkoe DJ, Klumperman J (2006), Presenilin-1-mediated retention of APP Derivatives in early biosynthetic compartments, Traffic, 7, 354-364.

Rabouille C, Klumperman J (2005), The maturing role of COPI vesicles in intra-Golgi transport, Nat Rev Mol Cell Biol, 6, 812-817.

Peden AA, Oorschot V, Hesser B, Austin CD, Scheller RH, Klumperman J (2004), Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins, J Cell Biol, 164, 1065-1076.

Koster AJ, Klumperman J (2003), Electron microscopy: stretching the resolution limits of imaging, Nat Rev Mol Cell Biol, ss6-ss10.

Sachse M, Urbé S, Oorschot V, Strous G, Klumperman J (2002), Bi-layered clathrin coats on endosomal vacuoles are involved in protein sorting towards lysosomes, Mol Biol Cell, 13, 1313-1328.

Martinez-Menarguez JA, Prekeris R, Oorschot V, Scheller RH, Slot JW, Geuze HJ, Klumperman J (2001), Peri-Golgi vesicles contain retrograde but not anterograde proteins consistent with the cisternal progression model of intra-Golgi transport, J Cell Biol, 155, 1213-1224.

Martinez-Menarguez J, Geuze HJ, Slot JW, Klumperman J (1999), Vesicular tubular clusters between ER and Golgi mediate concentration of soluble secretory proteins by exclusion from COPI-coated vesicles, Cell, 98, 81-90.

Dell'Angelica EC, Klumperman J, Stoorvogel W, Bonaficino JS (1998), Association of the AP-3 adaptor complex with clathrin, Science, 280, 431-434.

Klumperman J, Kuliawat R, Griffith J, Geuze HJ, Arvan P (1998), Mannose 6-phosphate receptors are sorted from immature secretory granules via AP-1, clathrin and syntaxin 6-positive vesicles, J Cell Biol, 141, 359-371.

Klumperman J, Hille A, Veenendaal T, Oorschot V, Stoorvogel W, von Figura K, Geuze HJ (1993), Differences in the endosomal distributions of the two mannose 6-phosphate receptors, J Cell Biol, 121, 997-1010.